DSM Criteria for Bipolar Disorder
The specific DSM-IV criteria for manic, hypomanic, major depressive, and mixed episodes are:
Manic Episode
A manic episode is a distinct period of abnormally and persistently elevated, expansive, or irritable mood lasting ≥ 1 week (or ? 1 week if hospitalization required), with ≥ 3 of the following symptoms present (4 if the mood is only irritable):
- Inflated self-esteem or grandiosity
- Decreased need for sleep (eg, feeling rested after only 3 hours of sleep)
- Unusual talkativeness
- Racing thoughts
- Distractibility
- Increased goal-directed activity (socially, at work or school, or sexually)
- Doing things that have a high potential for negative consequences, eg, unrestrained buying sprees, sexual indiscretions, or foolish business investments
To be considered a manic episode:
- Mood disturbance severe enough to cause noticeable difficulty at work, at school, or in usual social activities or relationships; to require hospitalization to prevent harm to self or others; or to trigger a break from reality (psychosis)
- Symptoms do not meet criteria for mixed episode (see below)
- Symptoms not due to direct effects of something else such as alcohol or drug use, medication, or a medical condition such as hyperthyroidism
Hypomanic Episode
A hypomanic episode is a distinct period of elevated, expansive, or irritable mood lasting ≥ 4 days and different from the usual nondepressed mood. During the period of disturbed mood, ≥ 3 of the following symptoms must be present (4 if the mood is only irritable):
- Inflated self-esteem or grandiosity
- Decreased need for sleep (eg, feeling rested after only 3 hours of sleep)
- Unusual talkativeness
- Racing thoughts
- Distractibility
- Increased goal-directed activity (socially, at work or school, or sexually)
- Doing things that have a high potential for negative consequences, eg, unrestrained buying sprees, sexual indiscretions, or unwise business investments
To be considered a hypomanic episode:
- Mood disturbance severe enough to cause a noticeable and uncharacteristic change in functioning
- Episode not severe enough to cause significant difficulty at work, at school, or in usual social activities or relationships; to require hospitalization; or to trigger a break from reality (psychosis)
- Symptoms do not meet criteria for mixed episode (see below)
- Symptoms not due to the direct effects of something else such as alcohol or drug use, medication, or a medical condition such as hyperthyroidism
Major Depressive Episode
Presence of ≥ 5 of the following symptoms over a 2-week period, with ≥ 1 being either depressed mood or loss of interest or pleasure, based either on patient report or observed by others:
- Depressed mood most of the day, nearly every day
- Diminished interest or feeling no pleasure in all, or almost all, activities most of the day, nearly every day
- Significant weight loss when not dieting, weight gain, or decrease or increase in appetite nearly every day
- Insomnia or increased desire to sleep nearly every day
- Either restlessness or slowed behavior that can be observed by others
- Fatigue or loss of energy nearly every day
- Feelings of worthlessness or excessive or inappropriate guilt nearly every day
- Diminished ability to think or concentrate, or indecisiveness, nearly every day
- Recurrent thoughts of death or suicide, or a suicide attempt
To be considered a major depressive episode:
- Symptoms do not meet criteria for a mixed episode (see below)
- Symptoms severe enough to cause noticeable difficulty in day-to-day activities, such as work, school, social activities, or relationships with others
- Symptoms not due to the direct effects of something else, such as drug abuse, medication, or a medical condition such as hyperthyroidism
- Symptoms not caused by grieving
Mixed Episode
- Criteria met for both a manic episode and a major depressive episode nearly every day during ≥ 1-week period
- Mood disturbance severe enough to cause noticeable difficulty at work, at school, or in usual social activities or relationships; to require hospitalization to prevent harm to self or others; or to cause a break from reality (psychosis)
- Symptoms not due to direct effects of something else, such as drug abuse, medication, or medical condition such as hyperthyroidism
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